2 Rheumatoid Arthritis Medication Tied to Decrease Threat of Parkinson’s

By Robert Preidt
HealthDay Reporter

FRIDAY, Jan. 28, 2022 (HealthDay Information) — Two rheumatoid arthritis medication present potential for decreasing the danger of Parkinson’s illness, new analysis exhibits.

Some earlier research have discovered that folks with rheumatoid arthritis have a decrease danger of Parkinson’s, and it was steered {that a} class of rheumatoid arthritis medication known as disease-modifying antirheumatic medication (DMARDs) might play a job in that decreased danger.

To be taught extra, researchers analyzed knowledge from 1000’s of sufferers in Finland.

The usage of most DMARDs — together with methotrexate, sulfasalazine, gold preparations or immunosuppressants — at the very least three years earlier than Parkinson’s illness prognosis was not related to the danger of the illness in these with rheumatoid arthritis, in accordance with the examine printed on-line Jan. 21 within the journal Neurology.

Nevertheless, the researchers did discover that rheumatoid arthritis sufferers who took the DMARDs chloroquine or hydroxychloroquine had a 26% decrease danger of Parkinson’s illness.

Each of those medication have an effect on the immune system and have been proven to have anti-Parkinson’s potential in animal research, in accordance with the researchers. However outcomes of animal research are sometimes completely different from these in people.

The new examine was led by Anne Paakinaho of the Faculty of Pharmacy on the College of Japanese Finland in Kuopio.

Her group known as for additional investigation of the medication’ doable protecting results towards Parkinson’s.

The examine — funded by the Michael J. Fox Basis for Parkinson’s Analysis — managed for size of time with rheumatoid arthritis, age, intercourse and different well being situations, akin to coronary heart illness and diabetes.

The danger components for Parkinson’s illness are unclear, the examine authors famous in a journal information launch.

Earlier research have linked rheumatoid arthritis with Parkinson’s. However they’ve yielded conflicting findings, with rheumatoid arthritis being related to both a decrease or increased danger of Parkinson’s.

Extra data

The Parkinson’s Basis has extra on Parkinson’s illness.

SOURCE: College of Japanese Finland, information launch, Jan. 24, 2022

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