Early research in cell cultures appeared to point that ivermectin might forestall COVID-19 from getting into cells, however that has not panned out in people, Hendrickson mentioned.
But, the drug continues to be touted by those that oppose COVID-19 vaccines, though no proof exists that it’s efficient in stopping or treating COVID-19, he mentioned.
For the examine, Hendrickson’s crew reviewed ivermectin-related calls to the Oregon Poison Middle in August. In all, 21 folks reported unwanted effects after taking the drug.
A lot of the studies got here from folks over 60 years of age. Eleven of the studies had been from individuals who took ivermectin to forestall COVID-19. The opposite 10 took the drug to deal with COVID-19 signs.
Amongst these taking ivermectin, three had a prescription from a physician or veterinarian, and 17 bought veterinary variations of the drug. The place the others received the drug is not recognized.
For most individuals, hostile signs developed inside two hours after taking a big, first-time dose of the drug. In six folks, signs developed over a number of days to weeks after repeated doses taken each different day or twice weekly. One particular person was additionally taking vitamin D to deal with or forestall COVID-19.
Six of the 21 had been hospitalized for poisonous results from ivermectin, and all mentioned they took the drug to forestall COVID-19, together with the three who had a prescription for the drug.
Of the six hospitalized, 4 had been handled in an intensive care unit, and none died. Amongst these hospitalized, gastrointestinal misery, confusion, ataxia, weak spot, low blood strain and seizures had been the most typical hostile unwanted effects.
For these not hospitalized, the most typical signs had been gastrointestinal misery, dizziness, confusion, imaginative and prescient signs and rash, the researchers discovered.
Hendrickson famous there’s no remedy for the unwanted effects of ivermectin. “It is only a matter of ready and supportive care,” he mentioned.
Since August, studies of significant unwanted effects from ivermectin have continued, though not as many, Hendrickson mentioned.
Dr. Robert Glatter, an emergency drugs doctor at Lenox Hill Hospital in New York Metropolis, mentioned, “Merely put, there is no such thing as a scientific use for prescribing ivermectin to deal with or forestall COVID-19. It is irresponsible and albeit harmful for well being care professionals to even take into account prescribing ivermectin for remedy or prevention of COVID-19.”