Remdesivir Could Maintain Unvaccinated Out of the Hospital: Research

Dec. 23, 2021 — The antiviral remdesivir, an intravenous drug given largely to significantly unwell COVID-19 sufferers in hospitals, might maintain unvaccinated individuals who change into contaminated out of the hospital if given on an outpatient foundation, a brand new examine says.

Researchers studied 562 unvaccinated individuals from September 2020 to April 2021, in response to the examine printed within the New England Journal of Drugs. The examine decided the chance of hospitalization or dying was 87% decrease in examine individuals who got remdesivir than individuals who acquired a placebo.

All individuals had been at excessive threat of creating extreme COVID-19 due to their age — they had been over 60 — or as a result of they’d an underlying medical situation resembling diabetes or weight problems.

An essential caveat: The findings are based mostly on knowledge collected earlier than the Delta variant surged final summer time or the Omicron variant surged late this yr, The Washington Submit reported.

The brand new examine says the drug might be useful in maintaining vaccinated in addition to unvaccinated individuals out of the hospital — an essential issue because the Omicron surge threatens to overwhelm well being methods world wide.

Remdesivir might be a boon for COVID-19 sufferers in components of the world that don’t have vaccines or for sufferers with immunocompromised methods.

“These knowledge present proof {that a} 3-day course of remdesivir might play a important function in serving to COVID-19 sufferers keep out of the hospital,” Robert L. Gottlieb, MD, PhD, the therapeutic lead for COVID-19 analysis at Baylor Scott & White Well being in Dallas, stated in a information launch from Gilead Prescribed drugs.

“Whereas our hospitals are prepared to help sufferers in want, prevention and early intervention are preferable to cut back the chance of illness development and permit sufferers not requiring oxygen to get well from house when applicable.”

Remdesivir was the primary antiviral for COVID-19 approved by the FDA. It was given to then-President Donald Trump when he was hospitalized with COVID-19 in October 2020.

Gilead launched the examine findings in September.

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