Whereas some nonetheless declare SARS-CoV-2 doesn’t truly exist, this appears to fly within the face of a number of well-established information. The virus has truly been photomicrographed,1,2 whole-genome sequences of the assorted strains can be found,3,4 and with the suitable credentials anybody can receive the dwell virus to conduct analysis.
Whereas I’m completely no fan of the U.S. Facilities for Illness Management and Prevention, they do develop the virus in cell tradition to make sure widespread availability for researchers who wish to research it.5 Examples of analysis the place you want the precise virus embrace antiviral analysis, vaccine improvement, virus stability analysis and pathogenesis analysis.6
What’s the Confusion?
At the least a part of the confusion seems to be rooted in how the time period “remoted” is outlined. Some insist a virus just isn’t remoted until it’s additionally purified, whereas others say a virus doesn’t should be purified so as to be “remoted.”
Steve Kirsch claims to have requested a number of consultants about this, noting that each one, together with Dr. Robert Malone and Dr. Li-Meng Yan, say that the virus has certainly been “remoted.” “So, it has been ‘remoted’ based on their perception in what the time period means,” Kirsch writes, including:7
“Others interpret the time period in a different way and would declare the virus hasn’t been remoted. In reality, based on their definition, no virus in historical past has ever been remoted. That’s essential to know. They use that as justification for his or her perception that there isn’t any virus right here since viruses don’t exist in any respect.”
When Kirsch requested his readers for enter, one identified:8
“The actual query is … has it been remoted from a HUMAN topic w/o passing it by means of (say) Monkey Kidney Cells? As a result of there may be loads of proof on the market that claims it hasn’t been remoted immediately (no intermediaries) from a HUMAN topic.”
In accordance with Kirsch, the scientists he spoke with didn’t agree that this was a priority, and “Sabine Hazan verified that the sequence of the virus obtained from ATCC [the American Type Culture Collection, a global resource center for reference microorganisms] matched precisely what she present in individuals who have the virus.”9
As famous in Hazan’s paper, “Detection of SARS-CoV-2 From Affected person Fecal Samples by Entire Genome Sequencing”:10
“Examine individuals underwent testing for SARS-CoV-2 from fecal samples by entire genome enrichment NGS [next-generation sequencing] (n = 14), and RT-PCR nasopharyngeal swab evaluation (n = 12).
The concordance of SARS-CoV-2 detection by enrichment NGS from stools with RT-PCR nasopharyngeal evaluation was 100%. Distinctive variants had been recognized in 4 sufferers, with a complete of 33 completely different mutations amongst these during which SARS-CoV-2 was detected by entire genome enrichment NGS.”
Germ Idea and Terrain Idea Each Have Benefit
As famous by impartial journalist and political analyst Jeremy Hammond in a March 2021 interview,11 the declare that SARS-CoV-2 has by no means been remoted and truly doesn’t exist in any respect is probably probably the most counterproductive arguments of the well being freedom motion.
By insisting that there isn’t any virus, and that COVID-19 is attributable to issues like 5G radiation alone, permits the mainstream media to dismiss fully official issues about electromagnetic subject publicity (EMF) and 5G — together with the chance that it would make some folks extra weak to infections.
Like Hammond, I imagine the pathogenesis of COVID-19 includes each germ concept and terrain concept, not only one or the opposite. “SARS-CoV-2 an infection is an inadequate however mandatory issue within the pathogenesis of COVID-19,” Hammond says, including that “the virus is consistently being remoted and entire genome sequenced by scientists all around the world.”12
That mentioned, environmental elements can clearly play a task, in that they will make you roughly predisposed to extreme an infection whenever you encounter this virus. This consists of EMFs, toxins like glyphosate, earlier vaccine accidents and way more.
Hammond argues that the “COVID-19 pandemic ought to be a wake-up name to the human inhabitants, and particularly the populations of developed nations, about the necessity to give attention to pure technique of sustaining good well being and dwelling in higher concord with our pure atmosphere.”
Certainly. And, as Hammond factors out, pathogenic problem is completely mandatory for basic good well being and powerful immunity. Once we defend ourselves an excessive amount of from on a regular basis pathogens, we make ourselves weak to persistent illnesses as a substitute.
SARS-CoV-2 Genome Sequencing From Italy
As for whether or not SARS-CoV-2 has been remoted and exists as a viral entity, the reply seems to be sure. For instance, an Italian paper13 revealed within the Journal of Virology, dated Might 18, 2020, detailed the isolation and full-length genome of the virus taken from COVID-19 sufferers in Italy:
“In the beginning of March 2020, the primary nasopharyngeal swabs optimistic for SARS-CoV-2 began to be detected within the Northern Japanese Area of Friuli-Venezia Giulia … Swab contents had been seeded on Vero E6 cells and monitored for cytopathic impact and by an RT-PCR protocol utilizing primers for the N area.
Cell tradition supernatants from passage 1 (P1) of 4 isolates had been collected, and RNA was extracted with QIAamp viral RNA minikit (Qiagen) and quantified with an in vitro-transcribed RNA customary … The amount and high quality of the RNA had been assessed … For every pattern, 100 ng of whole RNA was processed utilizing Zymo-Seq RiboFree ribosomal depletion library preparation equipment (Zymo Analysis).
All of the obtained libraries handed high quality test and had been quantified earlier than being pooled at equimolar focus and sequenced … Sequenced reads that handed the standard test (Phred rating ≥30) had been adaptor and high quality trimmed, and the remaining reads had been assembled de novo utilizing Megahit (v.1.2.9) with default parameter settings.
Megahit generated in all circumstances 7 contigs with greater than 1,000 bp and 100× protection; all of those assembled contigs had been in contrast (utilizing BLASTn) in opposition to all the nonredundant (nr) nucleotide and protein databases.
In all circumstances the longest and extra lined contigs had been recognized as MT019532.1,14 ‘Extreme acute respiratory syndrome coronavirus 2 isolate BetaCoV/Wuhan/IPBCAMS-WH-04/2019, full genome,’ with 99% id and 0 gaps.
The longer sequences had been named hCoV-19/Italy/FVG/ICGEB_S1, _S5, _S8, and _S9 and had been deposited in GISAID … Sequence evaluation confirmed an uneven protection alongside the SARS-CoV-2 genome, with a mean vary from 126 to 7,576 reads and a imply protection per pattern of 1,169× … Phylogenetic timber had been inferred utilizing the utmost probability technique …
The primary sequences deposited in GISAID (EPI_ISL_410545 and EPI_ISL_410546) had been collected in Rome from a Chinese language vacationer from Hubei province who obtained contaminated earlier than visiting Italy, and one other one (EPI_ISL_412974) was from a test-positive Italian citizen getting back from China.
Solely two sequences had been reported from the Lombardy cluster (EPI_ISL_412973 and EPI_ISL_413489). On this report 4 extra sequences from circumstances epidemiologically linked to northern Italy have been examined … Sequence evaluation confirmed a great protection alongside the SARS-CoV-2 genome for all 4 isolates.
Based mostly on the marker variant S D614G, all 4 sequences grouped within the Bavarian rooted subclade G, which is dominant in Europe, together with the sequence from Lombardy, however distinct from the three sequences talked about above originating immediately from China.
Intriguingly, the brand new isolates had been extra intently associated to EPI_ISL_412973, whereas EPI_ISL_413489 was extra distant. No proof might be discovered for the putative 382-nucleotide (nt) deletion in ORF8 detected in Singapore, which has been proposed to point an attenuated phenotype.”
SARS-CoV-2 Genome Sequencing From Germany
Equally, the entire genome sequence of the virus taken from a German lady has been revealed, this one within the journal Microbiology Useful resource Bulletins, in June 2020.
Right here, an oropharyngeal swab pattern from a feminine affected person who examined optimistic however had no signs on the time of the check was used to isolate the pressure.15 Desk 1 within the paper compares the nucleotide variants discovered within the sampled virus and people of a reference pressure already logged within the gene financial institution.
One other paper16 in Annals of Inside Drugs, revealed in August 2020, remoted the virus from ocular (eye) secretions of an Italian COVID affected person:17
“The affected person, a 65-year-old lady, travelled from Wuhan, China, to Italy on 23 January 2020 and was admitted on 29 January 2020, 1 day after symptom onset. At admission to the excessive isolation unit … she introduced with nonproductive cough, sore throat, coryza, and bilateral conjunctivitis. She had no fever till day 4, when fever (38 °C), nausea, and vomiting started.
An infection with SARS-CoV-2 was confirmed by performing real-time reverse transcription polymerase chain response (RT-PCR) assay on sputum samples (cycle threshold worth [Ct], 16.1) on the admission day, adopted by viral M gene sequencing (GenBank accession quantity MT008022), and virus isolation on Vero E6 cell line (2019-nCoV/Italy-INMI1).
The total genome sequence was obtained from both medical pattern or tradition isolate (GISAID accession numbers EPI_ISL_410545 and EPI_ISL_410546).”
Genome Sequencing From India and Colombia
SARS-CoV-2 has additionally been remoted from the urine of a COVID-19 affected person.18 A November 2020 paper19 sought to find out “whether or not varied medical specimens obtained from COVID-19 sufferers comprise the infectious virus,” and located SARS-CoV-2 RNA “in all naso/oropharyngeal swabs and saliva, urine and stool samples collected between Days 8 and 30 of the medical course.”
Viable SARS-CoV-2 was additionally discovered within the nasal washes of ferrets that had been inoculated with urine or stool from a COVID-19 affected person. The virus has additionally been remoted by researchers within the U.S.,20 China,21 India,22 Canada,23 Australia,24 Korea25 and Colombia.26 The Colombian paper reads partly:27
“Goal: To explain the isolation and characterization of an early SARS-CoV-2 isolate from the epidemic in Colombia. Supplies and strategies: A nasopharyngeal specimen from a COVID-19 optimistic affected person was inoculated on completely different cell strains.
To verify the presence of SARS-CoV-2 on cultures we used qRT-PCR, oblique immunofluorescence assay, transmission and scanning electron microscopy, and next-generation sequencing.
Outcomes: We decided the isolation of SARS-CoV-2 in Vero-E6 cells by the looks of the cytopathic impact three days post-infection and confirmed it by the optimistic leads to the qRT-PCR and the immunofluorescence with convalescent serum.
Transmission and scanning electron microscopy pictures obtained from contaminated cells confirmed the presence of buildings suitable with SARS-CoV-2. Lastly, a whole genome sequence obtained by next-generation sequencing allowed classifying the isolate as B.1.5 lineage.
The proof introduced on this article confirms the primary isolation of SARSCoV-2 in Colombia. As well as, it exhibits that this pressure behaves in cell tradition in an analogous option to that reported within the literature for different isolates and that its genetic composition is per the predominant variant on the earth.”
If Virus Exists, Why Aren’t Sure Research Achieved?
As talked about earlier, the precise virus is required so as to conduct sure research. Now, for the reason that virus does exist, we additionally ought to have the ability to conduct research to evaluate whether or not the COVID photographs trigger antibody dependent enhancement (ADE).
As instructed by Kirsch,28 “Give the vaccine to the animals, wait, then expose them to the virus” and see what occurs. Does it stop an infection and transmission, or does it make the animals extra vulnerable to an infection? If the animals obtained sicker, that might be proof of ADE, an issue that has plagued coronavirus vaccine analysis for many years.
It’s why we don’t have a vaccine in opposition to the frequent chilly, attributable to coronaviruses. Remarkably, this animal analysis has by no means been achieved for the COVID photographs. The query is why? Kirsch believes the reply is as a result of “no one desires to know the reply … The highest administration of the FDA is aware of it will kill the vaccine program in the event that they did this.”
Then again, the vaccinated, identical to the unvaccinated, are likely to expertise solely gentle signs with Omicron. So, maybe the photographs aren’t inflicting ADE (which may flip even a milder variant into one thing lethal).
Nevertheless, ADE is much from the one concern. Clearly, these photographs are related to a dramatically elevated threat of cardiovascular, cardiac and neurological issues. These too might be confirmed by means of animal research — reasonably than testing on our kids — and we wouldn’t even want the virus for these.
Both method, I imagine it’s scientifically correct to say that SARS-CoV-2 has been remoted, genetically sequenced, and that it exists as a pathogenic entity. Getting too far into the weeds of theories that refute the existence of viruses altogether will solely decelerate and hamper the reality motion reasonably than support it alongside, and I’d strongly discourage anybody from participating on this extremely unproductive narrative.